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HOW LIFE WORKS

A USER’S GUIDE TO THE NEW BIOLOGY

A bold effort to create a new language that forces a “rethinking” of “thinking itself.”

Generating a new language for the book of life.

Life is not all about tidy genetic blueprints; it is influenced by "messy and capricious" elements so many levels that genes are “just ingredients for creating a palette of...possibilities,” writes Ball, a former longtime editor at Nature and author of many books about science and nature. He first examines old biological tenets gone wrong, such as the notion that one gene is equal to one protein, or that correcting single gene mutations can “cure” most diseases. Language, writes the author, is the only “human technology” that bears any resemblance to the “mechanism of life...undoubtedly because it is a kind of ‘organic technology’ as much a part of our biological nature as is our flesh and blood, our minds, our cultures." Like life, when “you reduce it to its component parts, you lose its meaning.” Later, the author continues, “meaning carries a lot of baggage in biology, and you’ll rarely see it used in an academic text on the topic. But it’s a crucial concept, because it conveys a large part of what distinguishes life from other states of matter.” Many DNA sequences linked to complex traits and diseases are outside the “coding” genome,” and genes that generate fins can be “readily redirected to make an arm…Rapid phenotypic change is possible precisely because so little is demanded of the genes themselves.” In showing that complex life is more “emergent” than “programmed,” Ball takes on many conventional notions about biology. “We are at the beginning of a profound rethinking of how life works,” he writes. Evolution has consistently invented new ways of creating living beings, and it will continue to do so. “The challenge,” writes the author, “is to find a good way of talking about these vital stratagems,” and his latest book offers plenty of food for thought for scientists in disciplines from medicine to engineering.

A bold effort to create a new language that forces a “rethinking” of “thinking itself.”

Pub Date: Nov. 6, 2023

ISBN: 9780226826684

Page Count: 520

Publisher: Univ. of Chicago

Review Posted Online: Aug. 24, 2023

Kirkus Reviews Issue: Sept. 15, 2023

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THE ELEPHANTS OF THULA THULA

A heartwarming and inspiring story for animal lovers.

The third volume in the Elephant Whisperer series.

In this follow-up to An Elephant in My Kitchen, Malby-Anthony continues her loving portrait of the Thula Thula wildlife reserve, which she co-founded in 1998 with her late husband, South African conservationist Lawrence Anthony, who published the first book in the series, The Elephant Whisperer, in 2009. Following his death in 2012, Malby-Anthony sought to honor his legacy by continuing his vision “to create a massive conservancy in Zululand, incorporating our land and other small farms and community land into one great big game park.” At the same time, the elephants gave her “a sense of purpose and direction.” In the Zulu language, thula means quiet, and though the author consistently seeks to provide that calm to her charges, peace and tranquility are not always easy to come by at Thula Thula. In this installment, Malby-Anthony discusses many of the challenges faced by her and her staff, particularly during the Covid-19 pandemic. These included an aggressive, 2-ton rhino named Thabo; the profound loss felt by all upon the death of their elephant matriarch, Frankie; difficulty obtaining permits and the related risk of having to relocate or cull some of their animals; the fear of looting and fire due to civil unrest in the region; and the ongoing and potentially deadly struggles with poachers. Throughout, the author also shares many warm, lighthearted moments, demonstrating the deep bond felt among the humans and animals at the reserve and the powerful effects of the kindness of strangers. “We are all working in unity for the greater good, for the betterment of Thula Thula and all our wildlife….We are humbled by the generosity and love, both from our guests and friends, and from strangers all around the world,” writes the author. “People’s open-hearted support kept us alive in the darkest times.”

A heartwarming and inspiring story for animal lovers.

Pub Date: April 25, 2023

ISBN: 9781250284259

Page Count: 320

Publisher: St. Martin's

Review Posted Online: Feb. 22, 2023

Kirkus Reviews Issue: March 15, 2023

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THE RIGHT STUFF

Yes: it's high time for a de-romanticized, de-mythified, close-up retelling of the U.S. Space Program's launching—the inside story of those first seven astronauts.

But no: jazzy, jivey, exclamation-pointed, italicized Tom Wolfe "Mr. Overkill" hasn't really got the fight stuff for the job. Admittedly, he covers all the ground. He begins with the competitive, macho world of test pilots from which the astronauts came (thus being grossly overqualified to just sit in a controlled capsule); he follows the choosing of the Seven, the preparations for space flight, the flights themselves, the feelings of the wives; and he presents the breathless press coverage, the sudden celebrity, the glorification. He even throws in some of the technology. But instead of replacing the heroic standard version with the ring of truth, Wolfe merely offers an alternative myth: a surreal, satiric, often cartoony Wolfe-arama that, especially since there isn't a bit of documentation along the way, has one constantly wondering if anything really happened the way Wolfe tells it. His astronauts (referred to as "the brethren" or "The True Brothers") are obsessed with having the "right stuff" that certain blend of guts and smarts that spells pilot success. The Press is a ravenous fool, always referred to as "the eternal Victorian Gent": when Walter Cronkite's voice breaks while reporting a possible astronaut death, "There was the Press the Genteel Gent, coming up with the appropriate emotion. . . live. . . with no prompting whatsoever!" And, most off-puttingly, Wolfe presumes to enter the minds of one and all: he's with near-drowing Gus Grissom ("Cox. . . That face up there!—it's Cox. . . Cox knew how to get people out of here! . . . Cox! . . ."); he's with Betty Grissom angry about not staying at Holiday Inn ("Now. . . they truly owed her"); and, in a crude hatchet-job, he's with John Glenn furious at Al Shepard's being chosen for the first flight, pontificating to the others about their licentious behavior, or holding onto his self-image during his flight ("Oh, yes! I've been here before! And I am immune! I don't get into corners I can't get out of! . . . The Presbyterian Pilot was not about to foul up. His pipeline to dear Lord could not be clearer"). Certainly there's much here that Wolfe is quite right about, much that people will be interested in hearing: the P-R whitewash of Grissom's foul-up, the Life magazine excesses, the inter-astronaut tensions. And, for those who want to give Wolfe the benefit of the doubt throughout, there are emotional reconstructions that are juicily shrill.

But most readers outside the slick urban Wolfe orbit will find credibility fatally undermined by the self-indulgent digressions, the stylistic excesses, and the broadly satiric, anti-All-American stance; and, though The Right Stuff has enough energy, sass, and dirt to attract an audience, it mostly suggests that until Wolfe can put his subject first and his preening writing-persona second, he probably won't be a convincing chronicler of anything much weightier than radical chic.

Pub Date: Sept. 24, 1979

ISBN: 0312427565

Page Count: 370

Publisher: Farrar, Straus and Giroux

Review Posted Online: Oct. 13, 2011

Kirkus Reviews Issue: Sept. 1, 1979

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