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SIGNS OF LIFE

THE LANGUAGE AND MEANINGS OF DNA

Pollack (former dean of Columbia College and colleague of James D. Watson) takes the popular metaphor of DNA as language—and really runs with it. Pollack's thesis is that DNA, like language, is rich in multiple meanings, equipped with homonyms and synonyms. Furthermore, the genetic text should be seen in a historical context—some parts are archaic; others reflect more recent changes, the whole indicating where we came from as well as the diversity of the species today: The current effort to map and sequence the human genome constitutes only one sample of a text that varies from person to person. Pollack begins by explaining how a cell ``reads'' genetic text, taking us through the process of protein-binding to the regulatory sequences informing the actual gene. These initiate the instruction: ``Start here now.'' What follows is a gene ``sentence'' that says, ``Do this to that.'' But between the order and the execution come the myriad steps of unzipping the double helix; transcribing the DNA to messenger RNA; moving it to the body of the cell; and using the cell's machinery to translate the message into the production of a protein that executes the order. So much for the straightforward science-writing here: What Pollack also offers is a metatext—a commentary on how important it is for science and society to celebrate the diversity of the species and to avoid the Faustian trap of editing genetic texts in ways that would amount to a new eugenics. He has much to say about health-care reform, genetic testing, in-vitro fertilization, and the patenting of genes. Finally, he proposes a new paradigm: the model of biology as an exact science of atoms and molecules must be replaced by the recognition that we'll never be able to predict how genes combine to produce human behavior—a biological uncertainty principle. Cautionary and sober words that can well and truly inform current social, political, and scientific debates.

Pub Date: Jan. 19, 1994

ISBN: 0-395-64498-4

Page Count: 201

Publisher: Houghton Mifflin

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: Dec. 1, 1993

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LAB GIRL

Jahren transcends both memoir and science writing in this literary fusion of both genres.

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Award-winning scientist Jahren (Geology and Geophysics/Univ. of Hawaii) delivers a personal memoir and a paean to the natural world.

The author’s father was a physics and earth science teacher who encouraged her play in the laboratory, and her mother was a student of English literature who nurtured her love of reading. Both of these early influences engrossingly combine in this adroit story of a dedication to science. Jahren’s journey from struggling student to struggling scientist has the narrative tension of a novel and characters she imbues with real depth. The heroes in this tale are the plants that the author studies, and throughout, she employs her facility with words to engage her readers. We learn much along the way—e.g., how the willow tree clones itself, the courage of a seed’s first root, the symbiotic relationship between trees and fungi, and the airborne signals used by trees in their ongoing war against insects. Trees are of key interest to Jahren, and at times she waxes poetic: “Each beginning is the end of a waiting. We are each given exactly one chance to be. Each of us is both impossible and inevitable. Every replete tree was first a seed that waited.” The author draws many parallels between her subjects and herself. This is her story, after all, and we are engaged beyond expectation as she relates her struggle in building and running laboratory after laboratory at the universities that have employed her. Present throughout is her lab partner, a disaffected genius named Bill, whom she recruited when she was a graduate student at Berkeley and with whom she’s worked ever since. The author’s tenacity, hope, and gratitude are all evident as she and Bill chase the sweetness of discovery in the face of the harsh economic realities of the research scientist.

Jahren transcends both memoir and science writing in this literary fusion of both genres.

Pub Date: April 5, 2016

ISBN: 978-1-101-87493-6

Page Count: 336

Publisher: Knopf

Review Posted Online: Jan. 4, 2016

Kirkus Reviews Issue: Jan. 15, 2016

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THE ORDER OF TIME

As much a work of philosophy as of physics and full of insights for readers willing to work hard.

Undeterred by a subject difficult to pin down, Italian theoretical physicist Rovelli (Reality Is Not What It Seems: The Journey to Quantum Gravity, 2017, etc.) explains his thoughts on time.

Other scientists have written primers on the concept of time for a general audience, but Rovelli, who also wrote the bestseller Seven Brief Lessons on Physics, adds his personal musings, which are astute and rewarding but do not make for an easy read. “We conventionally think of time,” he writes, “as something simple and fundamental that flows uniformly, independently from everything else, uniformly from the past to the future, measured by clocks and watches. In the course of time, the events of the universe succeed each other in an orderly way: pasts, presents, futures. The past is fixed, the future open….And yet all of this has turned out to be false.” Rovelli returns again and again to the ideas of three legendary men. Aristotle wrote that things change continually. What we call “time” is the measurement of that change. If nothing changed, time would not exist. Newton disagreed. While admitting the existence of a time that measures events, he insisted that there is an absolute “true time” that passes relentlessly. If the universe froze, time would roll on. To laymen, this may seem like common sense, but most philosophers are not convinced. Einstein asserted that both are right. Aristotle correctly explained that time flows in relation to something else. Educated laymen know that clocks register different times when they move or experience gravity. Newton’s absolute exists, but as a special case in Einstein’s curved space-time. According to Rovelli, our notion of time dissolves as our knowledge grows; complex features swell and then retreat and perhaps vanish entirely. Furthermore, equations describing many fundamental physical phenomena don’t require time.

As much a work of philosophy as of physics and full of insights for readers willing to work hard.

Pub Date: May 18, 2018

ISBN: 978-0-7352-1610-5

Page Count: 256

Publisher: Riverhead

Review Posted Online: April 2, 2018

Kirkus Reviews Issue: April 15, 2018

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