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THE LAWS OF MEDICINE

FIELD NOTES FROM AN UNCERTAIN SCIENCE

A splendid exploration of how medicine might be transformed.

Oncologist and Pulitzer Prize winner Mukherjee (Medicine/Columbia Univ.; The Emperor of All Maladies: A Biography of Cancer, 2010) skillfully dives into the hidden side of medicine in this elaboration of the author’s 18-minute TED talk.

Easily consumed in a single sitting, this brief book concisely explains the author’s reasoning of why and how medicine asks its practitioners “to make perfect decisions with imperfect information.” The author builds a solid foundation demonstrating the genesis of his concept of establishing laws for the practice of medicine. Cogently moving through books that influenced his thinking and the effects of his medical training and numerous practical experiences with patients, Mukherjee guides readers through his thought process on establishing the laws. The author admits beginning slowly but then spending much of his time during medical school with his “odd preoccupation” researching laws governing his chosen profession. Mukherjee stumbled upon the first law, dealing with intuition, by chance. Another law, regarding issues of medical testing, was refined by his analysis of how data, which doesn’t fit accepted models of disease, such as “single patient anecdotes,” can point to new methods for interpreting test results. The author deftly examines the diverse personalities and subjects that have influenced his thinking (e.g., 16th-century Danish astronomer Tycho Brahe and early-20th-century physician and scientist Lewis Thomas, author of The Youngest Science); the positive effect of the 20th-century philosophy on therapeutic nihilism; and the utility of the magical laws embraced by the novice witch Hermione Granger of Harry Potter fame. This mininarrative, packed with complex ideas translated into easily accessible language and an engaging style, leaves the readers time to ponder the author’s ideas at greater length, and the result is a fascinating and illuminating trek through a beautiful mind.

A splendid exploration of how medicine might be transformed.

Pub Date: Oct. 13, 2015

ISBN: 978-1-4767-8484-7

Page Count: 120

Publisher: TED/Simon & Schuster

Review Posted Online: Aug. 5, 2015

Kirkus Reviews Issue: Aug. 15, 2015

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BETWEEN THE WORLD AND ME

NOTES ON THE FIRST 150 YEARS IN AMERICA

This moving, potent testament might have been titled “Black Lives Matter.” Or: “An American Tragedy.”

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The powerful story of a father’s past and a son’s future.

Atlantic senior writer Coates (The Beautiful Struggle: A Father, Two Sons, and an Unlikely Road to Manhood, 2008) offers this eloquent memoir as a letter to his teenage son, bearing witness to his own experiences and conveying passionate hopes for his son’s life. “I am wounded,” he writes. “I am marked by old codes, which shielded me in one world and then chained me in the next.” Coates grew up in the tough neighborhood of West Baltimore, beaten into obedience by his father. “I was a capable boy, intelligent and well-liked,” he remembers, “but powerfully afraid.” His life changed dramatically at Howard University, where his father taught and from which several siblings graduated. Howard, he writes, “had always been one of the most critical gathering posts for black people.” He calls it The Mecca, and its faculty and his fellow students expanded his horizons, helping him to understand “that the black world was its own thing, more than a photo-negative of the people who believe they are white.” Coates refers repeatedly to whites’ insistence on their exclusive racial identity; he realizes now “that nothing so essentialist as race” divides people, but rather “the actual injury done by people intent on naming us, intent on believing that what they have named matters more than anything we could ever actually do.” After he married, the author’s world widened again in New York, and later in Paris, where he finally felt extricated from white America’s exploitative, consumerist dreams. He came to understand that “race” does not fully explain “the breach between the world and me,” yet race exerts a crucial force, and young blacks like his son are vulnerable and endangered by “majoritarian bandits.” Coates desperately wants his son to be able to live “apart from fear—even apart from me.”

This moving, potent testament might have been titled “Black Lives Matter.” Or: “An American Tragedy.”

Pub Date: July 8, 2015

ISBN: 978-0-8129-9354-7

Page Count: 176

Publisher: Spiegel & Grau

Review Posted Online: May 5, 2015

Kirkus Reviews Issue: July 1, 2015

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WHEN BREATH BECOMES AIR

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...

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A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.

Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.

Pub Date: Jan. 19, 2016

ISBN: 978-0-8129-8840-6

Page Count: 248

Publisher: Random House

Review Posted Online: Sept. 29, 2015

Kirkus Reviews Issue: Oct. 15, 2015

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