A lively, clear, and comprehensive survey of who's who and what they're up to in the world of Artificial Intelligence (AI to cognoscenti) from science journalist Freedman. The term ``artificial intelligence'' calls up visions of the advanced computers and human-like robots familiar from hundreds of science fiction movies. The state of the art in AI today is probably best symbolized by Rodney Brooks' robot Attila, a six- inch metal ``cockroach'' scrambling over and around obstacles in the MIT AI labs founded by Marvin Minsky some 30 years ago. Not that the field has stagnated; in fact, the software-oriented approaches explored by Minsky and his fellow pioneers (John McCarthy, Seymour Papert) are considered somewhat old-hat by today's AI researchers, who have branched out into dozens of new directions. Japanese teams, with a mandate to develop a ``sixth generation'' computer, are exploring how living neurons actually transmit information, hoping to build up a detailed ``wiring diagram'' of the human brain. At UCLA, Chuck Taylor and David Jefferson are following an evolutionary strategy: creating computer programs with small random variations, then choosing the most successful in each batch as the ``parents'' for a new generation, in imitation of biological natural selection. Even the ``neural network'' approach to AI, which mechanically emulates the pattern recognition capabilities of the human brain (and which was temporarily discredited by Minsky and Papert in a 1969 critique), has been revived with some success at Stanford and Caltech. All these researchers have made interesting progress; Freedman lucidly summarizes the methods and results of their investigations, as well as the criticisms of such skeptics as John Searle and Roger Penrose. While much remains to be done to match even the more conservative prophecies of AI pioneers such as Minsky, the accomplishments to date, are often fascinating and shed light not only on the future of computers, but on the nature of intelligence itself.
Pub Date: April 1, 1994
ISBN: 0-671-76079-3
Page Count: 256
Publisher: Simon & Schuster
Review Posted Online: May 19, 2010
Kirkus Reviews Issue: Feb. 1, 1994
An exposition of the revolutionary changes in medicine coming in the next century as well as discussion of some of the ethical problems these will create. The distinguished Clark, professor emeritus of immunology at UCLA (Sex and the Origins of Death, 1996, etc.), attempts to explain to nonscientists the biology underlying molecular medicine. This is no small undertaking, and Clark is only partly successful. For the layperson, his work requires careful reading of dense text, mastery of a mysterious new vocabulary—``recombinant plasmids,'' ``antisense mRNA''—and study of complex diagrams. After these demanding biochemistry lessons, Clark turns to a fascinating discussion of what it all means in terms of health. He details the current state of gene therapy in treating cystic fibrosis and severe combined immune deficiency (the Bubble Boy disorder), in which copies of normal genes are being successfully introduced into the living cells of individuals with defective genes. In cancer, the ultimate goal of gene therapy is to alter or kill every tumor cell, and in AIDS to neutralize the effects of HIV. Clark, who is optimistic about reaching these goals, then devotes a chapter each to the profound effects on public health that DNA vaccination (injecting a gene from a pathogen, which would be more effective than today's vaccines) will bring in the next century and to the significance of the Human Genome Project, due to be completed shortly after the turn of the century. He clearly sees an educated public as the best defense against misuse of genetic information, for instance, altering a fetus's genetic makeup with the best of medical intentions but without knowing all the consequences of doing so. Although Clark insists that if one is to understand molecular medicine, one must first understand molecular biology, those who find his biology lectures too academic for comfort can still savor the well-wrought medical and ethical discussions.
Pub Date: Nov. 1, 1997
ISBN: 0-19-511730-1
Page Count: 240
Publisher: Oxford Univ.
Review Posted Online: May 19, 2010
Kirkus Reviews Issue: Sept. 15, 1997
In 1270, one year before the start of Marco Polo's fabled adventure, a Jewish merchant from the Adriatic port of Ancona set sail for the Orient; over 700 years later, his recently discovered account affords a rare and fascinating glimpse into the peoples, commerce, and thought of the 13th century. Selbourne, a former Oxford professor with an interest in Judaica, presents a fully annotated, very readable translation from the medieval Italian. It reveals Jacob d'Ancona as a savvy businessman, a scholar, a knowledgeable healer—and someone who never shies from disputation. Jacob sails to the eastern Mediterranean; journeys overland to Basra, where he attends the wedding of his son to a wealthy merchant's daughter; crosses the Arabian Sea, alighting on India's Malabar Coast; and then via Sumatra sails north to the Chinese port of Zaitun, the ``City of Light.'' Readers may be surprised to learn that Europeans of all stripes, as well as Saracens, or Muslims, had already been engaged in thriving trade with the Chinese for perhaps hundreds of years, Jewish merchants being among the most prominent. Zaitun itself was a Sodom of sorts: Its ``light'' is a consequence of the all-night commerce in human pleasures, which the pious Jacob abhors. But it is also a center of learning and a great agglomeration of peoples from the known medieval world. During his five-month sojourn, Jacob becomes involved in the intellectual and practical debates swirling around the city, which faced imminent invasion by Kublai Khan, to whom Polo would shortly become an advisor. Jacob's somewhat prolix disquisitions on piety and religion, the relationships among Jews, Christians, and Muslims, and the wisdom of confronting the Mongols earn him both admiration and enmity, and he must finally flee the city, though not without considerable financial success. An exciting, stimulating, and unique human document, and one that will no doubt become a much-trumpeted addition to the historical record. (50 b&w photos)
Pub Date: Nov. 13, 1997
ISBN: 0-316-17353-3
Page Count: 384
Publisher: Little, Brown
Review Posted Online: May 19, 2010
Kirkus Reviews Issue: Sept. 1, 1997
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