The how of cloning, beautifully told by optimists who believe that wise heads and good science will justify the whys.

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AFTER DOLLY

THE USES AND MISUSES OF HUMAN CLONING

This book from the “father” of the world’s first cloned animal ranges from autobiography to medical history to an extensive discussion of the policies and ethical issues raised by Dolly.

An undistinguished student when he arrived at agricultural college, Wilmut became fascinated there with embryology. He landed a summer job at an animal research station, supervised by leaders in reproductive science. That launched him into decades of work: freezing and thawing embryos; inserting genes to get animals to express useful drugs (“pharming”); and finally producing Dolly. Assisted by Daily Telegraph science editor Highfield, Wilmut graphically describes the process of transferring DNA from a mammary-gland cell of an adult ewe to an egg denuded of its nucleus, then implanting the embryo into a surrogate sheep; these pages are among the book’s high points. But no one should conclude that “now we can do it so much better and faster,” the authors aver. Although now more common, cloning is still a daunting process. Wasted eggs, failed pregnancies and deformed offspring reveal how complex and subtle are the steps in reproduction. For these reasons, Wilmut concludes that human cloning is not only unethical, but also impractical. He argues instead for creating blastocysts, the hollow, days-old spheres of cells lined with embryonic stem cells. These would make it possible, for example, to study hereditary diseases, to test treatments for them, maybe even to correct the defects that cause them. “A blastocyst is not a person,” the authors passionately contend. They hope that gradual growth in knowledge, the generation of useful applications and sheer familiarity with the science (here they make an apt comparison with in vitro fertilization technology) might bring around the naysayers, especially if strict regulation assures the highest ethical standards.

The how of cloning, beautifully told by optimists who believe that wise heads and good science will justify the whys.

Pub Date: June 12, 2006

ISBN: 0-393-06066-7

Page Count: 256

Publisher: Norton

Review Posted Online: May 20, 2010

Kirkus Reviews Issue: April 15, 2006

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Loads of good explaining, with reminders, time and again, of how much remains unknown, neatly putting the death of science...

A SHORT HISTORY OF NEARLY EVERYTHING

Bryson (I'm a Stranger Here Myself, 1999, etc.), a man who knows how to track down an explanation and make it confess, asks the hard questions of science—e.g., how did things get to be the way they are?—and, when possible, provides answers.

As he once went about making English intelligible, Bryson now attempts the same with the great moments of science, both the ideas themselves and their genesis, to resounding success. Piqued by his own ignorance on these matters, he’s egged on even more so by the people who’ve figured out—or think they’ve figured out—such things as what is in the center of the Earth. So he goes exploring, in the library and in company with scientists at work today, to get a grip on a range of topics from subatomic particles to cosmology. The aim is to deliver reports on these subjects in terms anyone can understand, and for the most part, it works. The most difficult is the nonintuitive material—time as part of space, say, or proteins inventing themselves spontaneously, without direction—and the quantum leaps unusual minds have made: as J.B.S. Haldane once put it, “The universe is not only queerer than we suppose; it is queerer than we can suppose.” Mostly, though, Bryson renders clear the evolution of continental drift, atomic structure, singularity, the extinction of the dinosaur, and a mighty host of other subjects in self-contained chapters that can be taken at a bite, rather than read wholesale. He delivers the human-interest angle on the scientists, and he keeps the reader laughing and willing to forge ahead, even over their heads: the human body, for instance, harboring enough energy “to explode with the force of thirty very large hydrogen bombs, assuming you knew how to liberate it and really wished to make a point.”

Loads of good explaining, with reminders, time and again, of how much remains unknown, neatly putting the death of science into perspective.

Pub Date: May 6, 2003

ISBN: 0-7679-0817-1

Page Count: 304

Publisher: Broadway

Review Posted Online: May 20, 2010

Kirkus Reviews Issue: April 1, 2003

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A tiny book, not much bigger than a pamphlet, with huge potential impact.

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NO ONE IS TOO SMALL TO MAKE A DIFFERENCE

A collection of articulate, forceful speeches made from September 2018 to September 2019 by the Swedish climate activist who was nominated for a Nobel Peace Prize.

Speaking in such venues as the European and British Parliaments, the French National Assembly, the Austrian World Summit, and the U.N. General Assembly, Thunberg has always been refreshingly—and necessarily—blunt in her demands for action from world leaders who refuse to address climate change. With clarity and unbridled passion, she presents her message that climate change is an emergency that must be addressed immediately, and she fills her speeches with punchy sound bites delivered in her characteristic pull-no-punches style: “I don’t want you to be hopeful. I want you to panic. I want you to feel the fear I feel every day. And then I want you to act.” In speech after speech, to persuade her listeners, she cites uncomfortable, even alarming statistics about global temperature rise and carbon dioxide emissions. Although this inevitably makes the text rather repetitive, the repetition itself has an impact, driving home her point so that no one can fail to understand its importance. Thunberg varies her style for different audiences. Sometimes it is the rousing “our house is on fire” approach; other times she speaks more quietly about herself and her hopes and her dreams. When addressing the U.S. Congress, she knowingly calls to mind the words and deeds of Martin Luther King Jr. and John F. Kennedy. The last speech in the book ends on a note that is both challenging and upbeat: “We are the change and change is coming.” The edition published in Britain earlier this year contained 11 speeches; this updated edition has 16, all worth reading.

A tiny book, not much bigger than a pamphlet, with huge potential impact.

Pub Date: Nov. 26, 2019

ISBN: 978-0-14-313356-8

Page Count: 112

Publisher: Penguin

Review Posted Online: Nov. 3, 2019

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