A readable pop-history account of medical research that turned out spectacularly.
A breathless history of a miraculous treatment.
Journalist Guthrie begins by explaining that the “Rh factor” is a protein related to blood type. About 85% of humans have Rh protein in their red blood cells; 15% don’t, making them Rh negative. If an Rh negative woman becomes pregnant by an Rh positive father, her fetus might be Rh positive. If so, the woman’s immune system, which has never encountered Rh, treats it as a foreign invader and generates antibodies. This takes time, so the first child is not affected, but the mother becomes “sensitized”—her immune system attacks future Rh positive fetuses, killing them or producing devastating anemia in the newborn. Doctors prevent it with a simple injection, called RhoGAM, approved in 1968. Guthrie tells this genuinely uplifting story through biographies of two Australians. John Gorman came to the U.S. in 1955, trained as a pathologist, and began investigating Rh disease, which, at the time, killed 10,000 American babies every year. Reading studies, he learned that when a particular antibody is present in blood, it inhibits the immune system from attacking its target foreign protein. He wondered if simply giving Rh antibody to a woman would prevent her sensitization. He was right, and Guthrie delivers an expert account of the eight years of often frustrating research that proved it. The author’s second hero is James Harrison, a bookkeeper who donated blood throughout his life, a total of 1,173 times. During lifesaving surgery as a teenager, he received many transfusions of Rh negative blood. Being positive himself, he developed titanic levels of Rh antibody, far more than the usual donor (RhoGAM is only obtained through donated blood). His blood has saved 2.4 million babies in Australia. Guthrie narrates her account like a novel, as her characters chat, think, brood, agonize, and ultimately triumph just as in a Hollywood movie.
A readable pop-history account of medical research that turned out spectacularly.Pub Date: Sept. 8, 2020
ISBN: 978-1-4197-4331-3
Page Count: 256
Publisher: Abrams
Review Posted Online: June 24, 2020
Kirkus Reviews Issue: July 15, 2020
BOOK REVIEW
BOOK REVIEW
BOOK REVIEW
An ebullient nature lover’s paean to birds.
A charming bird journey with the bestselling author.
In his introduction to Tan’s “nature journal,” David Allen Sibley, the acclaimed ornithologist, nails the spirit of this book: a “collection of delightfully quirky, thoughtful, and personal observations of birds in sketches and words.” For years, Tan has looked out on her California backyard “paradise”—oaks, periwinkle vines, birch, Japanese maple, fuchsia shrubs—observing more than 60 species of birds, and she fashions her findings into delightful and approachable journal excerpts, accompanied by her gorgeous color sketches. As the entries—“a record of my life”—move along, the author becomes more adept at identifying and capturing them with words and pencils. Her first entry is September 16, 2017: Shortly after putting up hummingbird feeders, one of the tiny, delicate creatures landed on her hand and fed. “We have a relationship,” she writes. “I am in love.” By August 2018, her backyard “has become a menagerie of fledglings…all learning to fly.” Day by day, she has continued to learn more about the birds, their activities, and how she should relate to them; she also admits mistakes when they occur. In December 2018, she was excited to observe a Townsend’s Warbler—“Omigod! It’s looking at me. Displeased expression.” Battling pesky squirrels, Tan deployed Hot Pepper Suet to keep them away, and she deterred crows by hanging a fake one upside down. The author also declared war on outdoor cats when she learned they kill more than 1 billion birds per year. In May 2019, she notes that she spends $250 per month on beetle larvae. In June 2019, she confesses “spending more hours a day staring at birds than writing. How can I not?” Her last entry, on December 15, 2022, celebrates when an eating bird pauses, “looks and acknowledges I am there.”
An ebullient nature lover’s paean to birds.Pub Date: April 23, 2024
ISBN: 9780593536131
Page Count: 320
Publisher: Knopf
Review Posted Online: Jan. 19, 2024
Kirkus Reviews Issue: Feb. 15, 2024
BOOK REVIEW
BOOK REVIEW
BOOK REVIEW
SEEN & HEARD
A virtuoso performance and an ode to an undervalued medium created by two talented artists.
The veteran actor, comedian, and banjo player teams up with the acclaimed illustrator to create a unique book of cartoons that communicates their personalities.
Martin, also a prolific author, has always been intrigued by the cartoons strewn throughout the pages of the New Yorker. So when he was presented with the opportunity to work with Bliss, who has been a staff cartoonist at the magazine since 1997, he seized the moment. “The idea of a one-panel image with or without a caption mystified me,” he writes. “I felt like, yeah, sometimes I’m funny, but there are these other weird freaks who are actually funny.” Once the duo agreed to work together, they established their creative process, which consisted of working forward and backward: “Forwards was me conceiving of several cartoon images and captions, and Harry would select his favorites; backwards was Harry sending me sketched or fully drawn cartoons for dialogue or banners.” Sometimes, he writes, “the perfect joke occurs two seconds before deadline.” There are several cartoons depicting this method, including a humorous multipanel piece highlighting their first meeting called “They Meet,” in which Martin thinks to himself, “He’ll never be able to translate my delicate and finely honed droll notions.” In the next panel, Bliss thinks, “I’m sure he won’t understand that the comic art form is way more subtle than his blunt-force humor.” The team collaborated for a year and created 150 cartoons featuring an array of topics, “from dogs and cats to outer space and art museums.” A witty creation of a bovine family sitting down to a gourmet meal and one of Dumbo getting his comeuppance highlight the duo’s comedic talent. What also makes this project successful is the team’s keen understanding of human behavior as viewed through their unconventional comedic minds.
A virtuoso performance and an ode to an undervalued medium created by two talented artists.Pub Date: Nov. 17, 2020
ISBN: 978-1-250-26289-9
Page Count: 272
Publisher: Celadon Books
Review Posted Online: Aug. 30, 2020
Kirkus Reviews Issue: Sept. 15, 2020
PERSPECTIVES
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