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BLOOD MATTERS

FROM INHERITED ILLNESS TO DESIGNER BABIES, HOW THE WORLD AND I FOUND OURSELVES IN THE FUTURE OF THE GENE

Credit Gessen with absorbing gobs of information, but this is a case in which a little learning may be a dangerous thing—for...

Unsettling medical memoir by a worried-but-still-well journalist who carries a breast-cancer gene.

Gessen (Ester and Ruzya: How My Grandmothers Survived Hitler's War and Stalin’s Peace, 2004, etc.) has steeped herself in genetics lore—and conjecture—in this wide-ranging account of genetic information past, present and future. Her own story is often the focus, as she relates the deaths of her mother and other relatives from breast or ovarian cancers and traces the inheritance of the BRCA1 gene to her great-great-grandmother. The mother of one adopted and one biological child, she is considering having another baby, but the genetic counselor she consults advises an ovariectomy and perhaps a double mastectomy. As Gessen wrestles with decision-making, the text increasingly leans toward a deterministic view of genetic destiny: The BRCA genes do not simply increase the odds of cancer; they cause it, with more stubborn forms occurring at an earlier age. This pessimism colors her account as she reviews the history of genetics from the horrors of eugenics and Nazism to the discovery of the gene for the sickle-cell trait, which persists in the population because it increases protection against malaria. There is much discussion of Ashkenazi Jews and their genetic load of diseases, as well as the genetic problems of other groups. She lauds the clinicians who work with Amish and Mennonite groups in Pennsylvania, developing diets to stave off the worse effects of inherited metabolic diseases. Gessen rightly addresses such issues as the reliability of the new genome-testing firms and the value of tests in cases like Huntington’s, where the disease is inevitable but as yet untreatable in carriers. But the text is again disturbing as she moves on to discuss controversial behavior-related genes, even pondering whether her young son’s Russian heritage may make him vulnerable to alcoholism.

Credit Gessen with absorbing gobs of information, but this is a case in which a little learning may be a dangerous thing—for the author and her readers.

Pub Date: April 1, 2008

ISBN: 978-0-15-101362-3

Page Count: 320

Publisher: Harcourt

Review Posted Online: June 24, 2010

Kirkus Reviews Issue: Feb. 1, 2008

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NIGHT

The author's youthfulness helps to assure the inevitable comparison with the Anne Frank diary although over and above the...

Elie Wiesel spent his early years in a small Transylvanian town as one of four children. 

He was the only one of the family to survive what Francois Maurois, in his introduction, calls the "human holocaust" of the persecution of the Jews, which began with the restrictions, the singularization of the yellow star, the enclosure within the ghetto, and went on to the mass deportations to the ovens of Auschwitz and Buchenwald. There are unforgettable and horrifying scenes here in this spare and sombre memoir of this experience of the hanging of a child, of his first farewell with his father who leaves him an inheritance of a knife and a spoon, and of his last goodbye at Buchenwald his father's corpse is already cold let alone the long months of survival under unconscionable conditions. 

The author's youthfulness helps to assure the inevitable comparison with the Anne Frank diary although over and above the sphere of suffering shared, and in this case extended to the death march itself, there is no spiritual or emotional legacy here to offset any reader reluctance.

Pub Date: Jan. 16, 2006

ISBN: 0374500010

Page Count: 120

Publisher: Hill & Wang

Review Posted Online: Oct. 7, 2011

Kirkus Reviews Issue: Jan. 15, 2006

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GENGHIS KHAN AND THE MAKING OF THE MODERN WORLD

A horde-pleaser, well-written and full of surprises.

“The Mongols swept across the globe as conquerors,” writes the appreciative pop anthropologist-historian Weatherford (The History of Money, 1997, etc.), “but also as civilization’s unrivaled cultural carriers.”

No business-secrets fluffery here, though Weatherford does credit Genghis Khan and company for seeking “not merely to conquer the world but to impose a global order based on free trade, a single international law, and a universal alphabet with which to write all the languages of the world.” Not that the world was necessarily appreciative: the Mongols were renowned for, well, intemperance in war and peace, even if Weatherford does go rather lightly on the atrocities-and-butchery front. Instead, he accentuates the positive changes the Mongols, led by a visionary Genghis Khan, brought to the vast territories they conquered, if ever so briefly: the use of carpets, noodles, tea, playing cards, lemons, carrots, fabrics, and even a few words, including the cheer hurray. (Oh, yes, and flame throwers, too.) Why, then, has history remembered Genghis and his comrades so ungenerously? Whereas Geoffrey Chaucer considered him “so excellent a lord in all things,” Genghis is a byword for all that is savage and terrible; the word “Mongol” figures, thanks to the pseudoscientific racism of the 19th century, as the root of “mongoloid,” a condition attributed to genetic throwbacks to seed sown by Mongol invaders during their decades of ravaging Europe. (Bad science, that, but Dr. Down’s son himself argued that imbeciles “derived from an earlier form of the Mongol stock and should be considered more ‘pre-human, rather than human.’ ”) Weatherford’s lively analysis restores the Mongols’ reputation, and it takes some wonderful learned detours—into, for instance, the history of the so-called Secret History of the Mongols, which the Nazis raced to translate in the hope that it would help them conquer Russia, as only the Mongols had succeeded in doing.

A horde-pleaser, well-written and full of surprises.

Pub Date: March 2, 2004

ISBN: 0-609-61062-7

Page Count: 320

Publisher: Crown

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: Dec. 1, 2003

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