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THE EMPEROR OF ALL MALADIES

A BIOGRAPHY OF CANCER

An inspiring account of a very personal battle against “the plague of our generation.”

The story of cancer, as well as a coming-of-age tale of a renowned oncologist.

Cancer physician Mukherjee (Medicine/Columbia Univ.) began this book in 2003 while completing a residency in medicine and graduate work in cancer immunology. He shapes the narrative as a heroic contest between two adversaries—cancer and the brave patients who fight for their lives, despite horrendous nausea from chemotherapy and other painful effects of the disease and the treatment. Only since the 1950s have cancer victims had a reasonable chance of surviving and returning to normal life, and even then surgical treatment often left patients disabled while halting but not stopping the spread of metastatic cancers. In addition, researchers had to consider the effects of radiation in destroying healthy tissue and causing leukemia and pernicious anemia. The side effects of both radiation and chemotherapy were frequently deadly. Mukherjee traces the refinement of treatments over the past 50 years and the development of early detection, as well as the growing understanding of the relationship between genetic abnormalities and environmental carcinogens in causing cancers. In 2005, significant advances and progress were noted by the scientific community. “The mortality for nearly every major form of cancer,” writes the author, “had continuously dropped for fifteen straight years.” Mukherjee also looks optimistically to the future when the Human Genome Project completes “The Cancer Genome Atlas,” which will become “a compendium of every gene mutated in the most common forms of cancer.”

An inspiring account of a very personal battle against “the plague of our generation.”

Pub Date: Nov. 16, 2010

ISBN: 978-1-4391-0795-9

Page Count: 592

Publisher: Scribner

Review Posted Online: June 16, 2010

Kirkus Reviews Issue: July 1, 2010

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LET ME FINISH

Graceful and deeply felt.

A collection of personal pieces, combined into an affecting memoir by longtime New Yorker editor Angell.

The author, a noted baseball writer (A Pitcher’s Story, 2001, etc.), has many intimate connections to the magazine Gardner Botsford once dubbed “The Comic Weekly,” in which most of these reminiscences originally appeared. His mother, Katherine, was the New Yorker’s fiction editor; years later, Angell held her former job—and occupied her office. His stepfather, E.B. White, was the magazine’s most important contributor during its most influential years. The memoir mostly concerns New Yorker colleagues and other remarkable people who have been a part of the author’s life. His father, lawyer Ernest Angell, lost Katherine to the younger White but over the years became a figure of immense importance to Roger. Angell loved his mother, loved White, loved his first wife (not much here about the cause of their 1960s divorce), loved his coworkers, loved his job. His portraits are really tributes, whether of the well-known William Maxwell, V.S. Pritchett, Harold Ross or William Shawn, or the lesser-known Botsford and Emily Hahn. Angell offers some New Yorker–insider tidbits (Ian Frazier mimicked Shawn’s voice so well that he could fool colleagues over the phone) and a bit more than you want to know about some of his aunts, one of whom wrote a book about Willa Cather. A dazzling story-within-a-story describes a 1940 round of golf with a mysterious woman who lost a valuable ring. The author seems uncertain how an iPod works but reveals an expertise with machine guns. His fickle memory frustrates and bemuses him. Sometimes he can recall only sensory images; sometimes the story unreeling in his mind skips, stops, fades, dissolves into something else. In several of his most appealing passages, he writes about the fictions that memory fashions.

Graceful and deeply felt.

Pub Date: May 8, 2006

ISBN: 0-15-101350-0

Page Count: 304

Publisher: Harcourt

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: March 1, 2006

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LETTER TO MY DAUGHTER

A slim volume packed with nourishing nuggets of wisdom.

Life lessons from the celebrated poet.

Angelou (A Song Flung Up to Heaven, 2002, etc.) doesn’t have a daughter, per se, but “thousands of daughters,” multitudes that she gathers here in a Whitmanesque embrace to deliver her experiences. They come in the shape of memories and poems, tools that readers can fashion to their needs. “Believing that life loves the liver of it, I have dared to try many things,” she writes, proceeding to recount pungent moments, stories in which her behavior sometimes backfired, and sometimes surprised even herself. Much of it is framed by the “struggle against a condition of surrender” or submission. She refuses to preach or consider her personal insights as generalized edicts. She is reminded of the charity that words and gestures bring and the liberation that comes with honesty. Lies, she notes, often spring out of fear. She cheated madness by counting her blessings. She is enlivened by those in love. She understands the uses and abuses of violence. Occasionally a bit of old-fashioned advice filters in, as during a commencement address/poem in which she urges the graduates to make a difference, to be present and accountable. The topics are mostly big, raw and exposed. Where is death’s sting? “It is here in my heart.” Overarching each brief chapter is the vital energy of a woman taking life’s measure with every step.

A slim volume packed with nourishing nuggets of wisdom.

Pub Date: Sept. 30, 2008

ISBN: 978-1-4000-6612-4

Page Count: 192

Publisher: Random House

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: Sept. 1, 2008

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