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THE EMPEROR OF ALL MALADIES

A BIOGRAPHY OF CANCER

An inspiring account of a very personal battle against “the plague of our generation.”

The story of cancer, as well as a coming-of-age tale of a renowned oncologist.

Cancer physician Mukherjee (Medicine/Columbia Univ.) began this book in 2003 while completing a residency in medicine and graduate work in cancer immunology. He shapes the narrative as a heroic contest between two adversaries—cancer and the brave patients who fight for their lives, despite horrendous nausea from chemotherapy and other painful effects of the disease and the treatment. Only since the 1950s have cancer victims had a reasonable chance of surviving and returning to normal life, and even then surgical treatment often left patients disabled while halting but not stopping the spread of metastatic cancers. In addition, researchers had to consider the effects of radiation in destroying healthy tissue and causing leukemia and pernicious anemia. The side effects of both radiation and chemotherapy were frequently deadly. Mukherjee traces the refinement of treatments over the past 50 years and the development of early detection, as well as the growing understanding of the relationship between genetic abnormalities and environmental carcinogens in causing cancers. In 2005, significant advances and progress were noted by the scientific community. “The mortality for nearly every major form of cancer,” writes the author, “had continuously dropped for fifteen straight years.” Mukherjee also looks optimistically to the future when the Human Genome Project completes “The Cancer Genome Atlas,” which will become “a compendium of every gene mutated in the most common forms of cancer.”

An inspiring account of a very personal battle against “the plague of our generation.”

Pub Date: Nov. 16, 2010

ISBN: 978-1-4391-0795-9

Page Count: 592

Publisher: Scribner

Review Posted Online: June 16, 2010

Kirkus Reviews Issue: July 1, 2010

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NIGHT

The author's youthfulness helps to assure the inevitable comparison with the Anne Frank diary although over and above the...

Elie Wiesel spent his early years in a small Transylvanian town as one of four children. 

He was the only one of the family to survive what Francois Maurois, in his introduction, calls the "human holocaust" of the persecution of the Jews, which began with the restrictions, the singularization of the yellow star, the enclosure within the ghetto, and went on to the mass deportations to the ovens of Auschwitz and Buchenwald. There are unforgettable and horrifying scenes here in this spare and sombre memoir of this experience of the hanging of a child, of his first farewell with his father who leaves him an inheritance of a knife and a spoon, and of his last goodbye at Buchenwald his father's corpse is already cold let alone the long months of survival under unconscionable conditions. 

The author's youthfulness helps to assure the inevitable comparison with the Anne Frank diary although over and above the sphere of suffering shared, and in this case extended to the death march itself, there is no spiritual or emotional legacy here to offset any reader reluctance.

Pub Date: Jan. 16, 2006

ISBN: 0374500010

Page Count: 120

Publisher: Hill & Wang

Review Posted Online: Oct. 7, 2011

Kirkus Reviews Issue: Jan. 15, 2006

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GENGHIS KHAN AND THE MAKING OF THE MODERN WORLD

A horde-pleaser, well-written and full of surprises.

“The Mongols swept across the globe as conquerors,” writes the appreciative pop anthropologist-historian Weatherford (The History of Money, 1997, etc.), “but also as civilization’s unrivaled cultural carriers.”

No business-secrets fluffery here, though Weatherford does credit Genghis Khan and company for seeking “not merely to conquer the world but to impose a global order based on free trade, a single international law, and a universal alphabet with which to write all the languages of the world.” Not that the world was necessarily appreciative: the Mongols were renowned for, well, intemperance in war and peace, even if Weatherford does go rather lightly on the atrocities-and-butchery front. Instead, he accentuates the positive changes the Mongols, led by a visionary Genghis Khan, brought to the vast territories they conquered, if ever so briefly: the use of carpets, noodles, tea, playing cards, lemons, carrots, fabrics, and even a few words, including the cheer hurray. (Oh, yes, and flame throwers, too.) Why, then, has history remembered Genghis and his comrades so ungenerously? Whereas Geoffrey Chaucer considered him “so excellent a lord in all things,” Genghis is a byword for all that is savage and terrible; the word “Mongol” figures, thanks to the pseudoscientific racism of the 19th century, as the root of “mongoloid,” a condition attributed to genetic throwbacks to seed sown by Mongol invaders during their decades of ravaging Europe. (Bad science, that, but Dr. Down’s son himself argued that imbeciles “derived from an earlier form of the Mongol stock and should be considered more ‘pre-human, rather than human.’ ”) Weatherford’s lively analysis restores the Mongols’ reputation, and it takes some wonderful learned detours—into, for instance, the history of the so-called Secret History of the Mongols, which the Nazis raced to translate in the hope that it would help them conquer Russia, as only the Mongols had succeeded in doing.

A horde-pleaser, well-written and full of surprises.

Pub Date: March 2, 2004

ISBN: 0-609-61062-7

Page Count: 320

Publisher: Crown

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: Dec. 1, 2003

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