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CRISPR

Science literally on the cutting edge, offering prospects of wonder and terror in equal measure.

A provocative report on world-changing developments promised by a dawning breakthrough in biotechnology.

Ridge first goes over the ins and outs of chromosomes and genomes, then explains how certain clusters of “palindromic repeats” found in the DNA of single-celled creatures can be employed to edit with precision any cell’s genetic “instruction manual.” Though just missing the onset of the COVID-19 pandemic, she goes on to explore the technique’s current and potential uses and misuses. The former include creating better medicines, cures for cancer and other systemic diseases, new plant varieties, and better livestock; the latter, scrambling ecological balances, cooking up frightening bioweapons, and “Playing God” with human germlines to make designer babies. In general she comes down on the positive side (if for no other reason than that it’s too late to get the cat back into the bag) but doesn’t skimp on laying out complications and quandaries for readers to chew over in formulating their own views. She leavens the hefty informational load as best she can (“The genetic similarity between a human and a banana is 60%”), and Boersma supplies a generous array of staid but lucid diagrams, schematics, and infographics in support. Though it is marketed as a book for readers 14 and up, both graphic design and complexity of language seem to suit it better for middle schoolers. 

Science literally on the cutting edge, offering prospects of wonder and terror in equal measure. (sources, resource lists, index) (Nonfiction. 12-14)

Pub Date: Sept. 8, 2020

ISBN: 978-1-77321-424-5

Page Count: 116

Publisher: Annick Press

Review Posted Online: May 16, 2020

Kirkus Reviews Issue: July 1, 2020

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HUMAN BODY THEATER

It’s a lot to take in at one sitting, but this anatomical extravaganza really gets to the heart of the matter. Not to...

A theatrical introduction to human anatomy, as well-choreographed as it is informative.

In 11 “Acts” hosted con brio by a skeletal impresario (“Bring out the lungs!”), Wicks parades a revue of body systems across a curtained stage. It’s a full program, with a teeming supporting cast from Dopamine to Diaphragm, Golgi Body to Gastroenteritis joining more-familiar headliners. The presentation opens with a zoom down to the cellular and even molecular levels to lay foundations for later macro and micro views of digestion, infection, and disease. Following this, the five senses (only five), the “dance of the oxygen fairies,” allergic reactions, and other anatomical processes that make up each system’s major components, most sporting cheery emoji-style faces, expressively demonstrate their respective functions. The reproductive system’s named parts deliver a frank but visually discreet turn with descriptions of erections and fertilization but no direct depictions, and it stops with the onset of puberty. The performances are enhanced by labeled diagrams, pitches on relevant topics from the importance of immunization and proper nutrition to synonyms for “fart,” and lists of important words and further resources. A few miscues aside (no, the speed of sound is not invariant), it’s a grand show, with a logically placed intermission following a peek into the bladder and a literal “wrap” at the end as the emcee puts herself together from inside out.

It’s a lot to take in at one sitting, but this anatomical extravaganza really gets to the heart of the matter. Not to mention the guts, nerves, veins, bones…. (glossary, bibliography) (Graphic nonfiction. 12-14)

Pub Date: Oct. 6, 2015

ISBN: 978-1-62672-277-4

Page Count: 240

Publisher: First Second

Review Posted Online: July 21, 2015

Kirkus Reviews Issue: Aug. 15, 2015

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BEASTLY BRAINS

EXPLORING HOW ANIMALS THINK, TALK, AND FEEL

The book’s high-interest topic is ill-served by its execution.

An exploration of animal intelligence.

Castaldo opens with a discussion of brainpower before summarizing historical thinking on animal cognition and then presenting evidence of it, in the form of a dizzying array of experiments on such subtopics as decision-making, empathy, a sense of fairness, and communication, among others. Candy-colored pastel shades and striking photographs make flipping the pages a pleasure, but actually reading them is something of a chore. Sidebars often appear out of sequence with the text and are of varying levels of utility, as is also the case with photo captions. Low points include a reference to the author’s middle school report on dolphins and a photograph of a dolphin alone in a tank that’s labeled, “A dolphin at the National Aquarium is studied by cognitive researchers.” Chapters are broken up into subtopics with catchy headings (“The Hive Brain”; “Emo Rats”) except when they are not, as with a relatively lengthy discussion of interspecies communication that wanders from bonobos to dolphins to Peter Gabriel to orangutans. The book’s sense of its audience is uncertain. Profligate use of exclamation points and simplistic “what would you do” scenarios seem geared to younger readers, while the un-glossed use of such terms as “habeas corpus” and “prosocial,” as well as a conceptually complex model of brain processing, assumes a fairly sophisticated audience.

The book’s high-interest topic is ill-served by its execution. (resources, glossary, source notes, bibliography, index) (Nonfiction. 12-14)

Pub Date: Feb. 7, 2017

ISBN: 978-0-544-63335-3

Page Count: 160

Publisher: HMH Books

Review Posted Online: Dec. 25, 2016

Kirkus Reviews Issue: Jan. 15, 2017

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